New Video
Autism: A Medical Condition Conference
Ottawa University
Dr. Derrick MacFabe
A Must View!
"The Self Centred Bug":
Can Aquired Infection Influence Brain Function and Behaviour in Autism?
This video was made possible thanks to the generous donation of Dapasoft
The lecture examines the possible role of infectious agents in the causes and symptoms of
neurodevelopmental disorders, with ASD as a key focus.
It discusses the effects of a series of infective and dietary agents of increasing incidence,
which are capable of inducing brain changes and complex behaviours
(i.e. aggression, biting, food craving, social impairment, hyperactivity, obsessive compulsive activity, sensory sensitivity)
in humans and experimental animals.
Dr. MacFabe presents his current research examining the ability of a panel of gut bacterial metabolic products
(i.e. short chain fatty acids) associated with antibiotic induced diarrhea,
and their ability to produce brain neuroinflammatory and behavioural changes
closely resembling those found in ASDs.
It discusses the hypothesis that ASDs are produced by opportunistic pre or post-natal
antibiotic resistant gastrointestinal infections in sensitive sub populations.
Exceptional Parent Magazine's Article by Dr. MacFabe
Autism Spectrum Disorders (ASD) are a rapidly increasing problem in western society.
Autism is a spectrum of severe neurodevelopmental disorders, frequently consisting of profound language impairment, repetitive motor behaviors, impaired socialization, sensory disturbances, severely restricted interests, and self-injury.
Seizure disorders also frequently accompanies autism.
The prevalence of autism is now 1 in 150.
This alarming increase, rising from between seven and 20 per thousand per 10,000 just a few decades ago, cannot be accounted for merely by increasing surveillance.
Click here to read full article
Dr. MacFabe is Assistant Professor and Director of the Kilee Patchell-Evans Autism Research Group,
Departments of Psychology (Neuroscience) and Psychiatry (Division of Developmental Disabilities) at the Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada.
Click here to read published paper in Behavioural Brain Research
Click here to read published paper in American Journal of Biochemistry and Biotechnology
Click here to read published paper in Neuro Pharmacology
Click Here to visit The Kilee Patchell-Evans Autism Research Group website
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